Nathan R. Tykocki, Ph.D.
Principal Investigator
Exploring the roles of ion channels as signaling regulators in the urinary bladder urothelium, detrusor muscle, vasculature, and sensory nerves.
How do we feel the need to go?
Can we alter bladder sensation without changing bladder function?
What is the sensor of bladder fullness?
We explore urinary bladder physiology to learn how sensory nerves and blood vessels control bladder function.
Our Team
Our Research
Click on the picture to learn more about the current and future projects championed by the lab (under construction)
New Tools for Bladder Physiology Research
PI: Tykocki & Hennig
Design, development and fabrication of new devices aimed at looking at bladder function from a higher orbit.
Bladder Blood Flow as a Regulator of Bladder Function
PI: Tykocki
Understanding how the unique properties of the urinary bladder vasculature regulate bladder function.
TRPV1 Channels in Stress-induced Bladder Dysfunction in Children
PI: Tykocki & Mingin
Investigating how the duration/intensity of social stress causes bladder dysfunction and determining the role TRPV1 channels play in its progression.
Stress, Strain, and Bladder Sensation
PI: Tykocki & Roccabianca
Exploring how the extracellular matrix alters transduction of bladder fullness to the brain.