Publications

Note: Clicking on the “PMID” or “PMC” number will take you to the full text, where available.

  1. Broemer, E, Saxena, P, Bartolone, S, Hennig, G, Herrera, GM, Zwaans, B et al.. Modeling bladder mechanics with 4D reconstruction of murine ex vivo bladder filling. Biomech Model Mechanobiol. 2024; :. doi: 10.1007/s10237-024-01914-7. PubMed PMID:39741201 .
  2. Hennig, G, Saxena, P, Broemer, E, Herrera, GM, Roccabianca, S, Tykocki, NR et al.. Quantifying whole bladder biomechanics using the novel pentaplanar reflected image macroscopy system. Biomech Model Mechanobiol. 2023;22 (5):1685-1695. doi: 10.1007/s10237-023-01727-0. PubMed PMID:37249760 PubMed Central PMC10511590.
  3. Jones, BM, Mingin, GC, Tykocki, NR. The mast cell stimulator compound 48/80 causes urothelium-dependent increases in murine urinary bladder contractility. Am J Physiol Renal Physiol. 2023;325 (1):F50-F60. doi: 10.1152/ajprenal.00116.2023. PubMed PMID:37199916 PubMed Central PMC10292985.
  4. Saxena, P, Broemer, E, Herrera, GM, Mingin, GC, Roccabianca, S, Tykocki, NR et al.. Compound 48/80 increases murine bladder wall compliance independent of mast cells. Sci Rep. 2023;13 (1):625. doi: 10.1038/s41598-023-27897-6. PubMed PMID:36635439 PubMed Central PMC9837046.
  5. Kowalewska, PM, Fletcher, J, Jackson, WF, Brett, SE, Kim, MS, Mironova, GY et al.. Genetic ablation of smooth muscle KIR2.1 is inconsequential to the function of mouse cerebral arteries. J Cereb Blood Flow Metab. 2022;42 (9):1693-1706. doi: 10.1177/0271678X221093432. PubMed PMID:35410518 PubMed Central PMC9441723.
  6. Jones, BM, Mingin, GC, Tykocki, NR. Histamine receptors rapidly desensitize without altering nerve-evoked contractions in murine urinary bladder smooth muscle. Am J Physiol Renal Physiol. 2022;322 (3):F268-F279. doi: 10.1152/ajprenal.00355.2021. PubMed PMID:35073211 PubMed Central PMC8858670.
  7. Tuttle, TG, Lujan, HL, Tykocki, NR, DiCarlo, SE, Roccabianca, S. Remodeling of extracellular matrix in the urinary bladder of paraplegic rats results in increased compliance and delayed fiber recruitment 16 weeks after spinal cord injury. Acta Biomater. 2022;141 :280-289. doi: 10.1016/j.actbio.2022.01.015. PubMed PMID:35032719 PubMed Central PMC8898290.
  8. Miron, TR, Flood, ED, Tykocki, NR, Thompson, JM, Watts, SW. Identification of Piezo1 channels in perivascular adipose tissue (PVAT) and their potential role in vascular function. Pharmacol Res. 2022;175 :105995. doi: 10.1016/j.phrs.2021.105995. PubMed PMID:34818570 PubMed Central PMC9301055.
  9. Turco, AE, Oakes, SR, Keil Stietz, KP, Dunham, CL, Joseph, DB, Chathurvedula, TS et al.. A mechanism linking perinatal 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure to lower urinary tract dysfunction in adulthood. Dis Model Mech. 2021;14 (7):. doi: 10.1242/dmm.049068. PubMed PMID:34318329 PubMed Central PMC8326766.
  10. Tykocki, NR, Monson, FC. Excitability and contractility in arterioles and venules from the urinary bladder. Curr Top Membr. 2020;85 :301-326. doi: 10.1016/bs.ctm.2020.01.003. PubMed PMID:32402643 PubMed Central PMC7716117.
  11. Jones, BM, Tykocki, NR. New direct evidence that histamine augments bladder sensory outflow during filling is nothing to sneeze at. Am J Physiol Renal Physiol. 2020;318 (2):F455-F456. doi: 10.1152/ajprenal.00581.2019. PubMed PMID:31904288 PubMed Central PMC7052655.
  12. Tykocki, NR, Heppner, TJ, Dalsgaard, T, Bonev, AD, Nelson, MT. The KV 7 channel activator retigabine suppresses mouse urinary bladder afferent nerve activity without affecting detrusor smooth muscle K+ channel currents. J Physiol. 2019;597 (3):935-950. doi: 10.1113/JP277021. PubMed PMID:30536555 PubMed Central PMC6355639.
  13. Tykocki, NR, Heppner, TJ, Erickson, CS, van Batavia, J, Vizzard, MA, Nelson, MT et al.. Development of stress-induced bladder insufficiency requires functional TRPV1 channels. Am J Physiol Renal Physiol. 2018;315 (6):F1583-F1591. doi: 10.1152/ajprenal.00231.2018. PubMed PMID:30089031 PubMed Central PMC6336983.
  14. Tykocki, NR, Boerman, EM, Jackson, WF. Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles. Compr Physiol. 2017;7 (2):485-581. doi: 10.1002/cphy.c160011. PubMed PMID:28333380 PubMed Central PMC5575875.
  15. Longden, TA, Dabertrand, F, Koide, M, Gonzales, AL, Tykocki, NR, Brayden, JE et al.. Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow. Nat Neurosci. 2017;20 (5):717-726. doi: 10.1038/nn.4533. PubMed PMID:28319610 PubMed Central PMC5404963.
  16. Tykocki, NR, Bonev, AD, Longden, TA, Heppner, TJ, Nelson, MT. Inhibition of vascular smooth muscle inward-rectifier K+ channels restores myogenic tone in mouse urinary bladder arterioles. Am J Physiol Renal Physiol. 2017;312 (5):F836-F847. doi: 10.1152/ajprenal.00682.2016. PubMed PMID:28148533 PubMed Central PMC5451557.
  17. Heppner, TJ, Tykocki, NR, Hill-Eubanks, D, Nelson, MT. Transient contractions of urinary bladder smooth muscle are drivers of afferent nerve activity during filling. J Gen Physiol. 2016;147 (4):323-35. doi: 10.1085/jgp.201511550. PubMed PMID:26976828 PubMed Central PMC4810069.
  18. Moon, TM, Tykocki, NR, Sheehe, JL, Osborne, BW, Tegge, W, Brayden, JE et al.. Synthetic Peptides as cGMP-Independent Activators of cGMP-Dependent Protein Kinase Iα. Chem Biol. 2015;22 (12):1653-61. doi: 10.1016/j.chembiol.2015.11.005. PubMed PMID:26687482 PubMed Central PMC4703045.
  19. Mingin, GC, Heppner, TJ, Tykocki, NR, Erickson, CS, Vizzard, MA, Nelson, MT et al.. Social stress in mice induces urinary bladder overactivity and increases TRPV1 channel-dependent afferent nerve activity. Am J Physiol Regul Integr Comp Physiol. 2015;309 (6):R629-38. doi: 10.1152/ajpregu.00013.2015. PubMed PMID:26224686 PubMed Central PMC4591369.
  20. Tykocki, NR, Nelson, MT. Location, Location, Location: Juxtaposed calcium-signaling microdomains as a novel model of the vascular smooth muscle myogenic response. J Gen Physiol. 2015;146 (2):129-32. doi: 10.1085/jgp.201511468. PubMed PMID:26216858 PubMed Central PMC4516781.
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